Scand J Gastroenterol 34 — Notably, 3 pregnancies occurred during the study period. Instead, an improvement in sperm motility and vitality during anti-TNF treatment was shown in that review. Vital Health Stat ; Reprinted from Olsen and colleagues 12 with permission from the American Gastroenterological Fulminant ulcerative colitis in late pregnancy and the puerperium. However most would recommend caution and to stop the drug at least 4 months prior to conception. Gut 54 —
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Infertility in men with inflammatory bowel disease
This finding was confirmed by Johnson and colleagues 13 who showed a It is also defined in specific terms as failure to conceive after a year of regular intercourse without contraception. Methotrexate may cause reversible oligospermia in men. References in review articles were used if relevant. Invited manuscript Specialty Type:
Active disease seems to affect male reproductive and sexual function[ 15 , 16 ]. Sperm banking should be offered to patients who plan to undergo proctocolectomy, because postoperative anejaculation, despite its low incidence, is a potential irreversible complication. Gut 52 — Effects of 6-mercaptopurine treatment on sperm production and reproductive performance: The biologics may be associated with reduced sperm motility which may impact on fertility. Thus, control of IBD activity is recommended for men planning to conceive.
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Ulcerative Colitis - artikel-web.info Forum
Surgery for inflammatory bowel disease. Unlike other sulfonamides, bilirubin displacement, and therefore kernicterus, does not occur in the infant. AZA and its active metabolite 6-mercaptopurine 6-MP are widely used as adjunctive therapy in IBD and as corticosteroid-sparing therapies although they are unapproved therapies for IBD[ 47 ]. Andrologia 35 —